{"id":599,"date":"2018-05-03T09:37:33","date_gmt":"2018-05-03T09:37:33","guid":{"rendered":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/?page_id=599"},"modified":"2018-05-15T09:09:31","modified_gmt":"2018-05-15T09:09:31","slug":"anopheles-darlingi","status":"publish","type":"page","link":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/?page_id=599","title":{"rendered":"Anopheles darlingi"},"content":{"rendered":"<div style=\"width: 210px\" class=\"wp-caption alignright\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/www.scientistsagainstmalaria.net\/sites\/default\/files\/styles\/full_post\/public\/darlingi.jpg?resize=200%2C116\" width=\"200\" height=\"116\" class=\"size-medium\" \/><p class=\"wp-caption-text\">(source : Scientist Against Malaria)<\/p><\/div>\n<p><em>Anopheles darlingi<\/em> is a major malaria vector in the Americas. Its broad geographical distribution, ranging from southern Mexico to northern Argentina, is coupled with a high morphological, behavioral and genetic diversity. Support for considerable genetic variation within this taxon comes from the analysis of polytene chromosomes, isozymes, as well as nuclear and mitochondrial DNA markers. Its genome was sequenced in 2010.<\/p>\n<p>(source &#038; for more information : <a href=\"http:\/\/www.scientistsagainstmalaria.net\/vector\/anopheles-darlingi\" rel=\"noopener\" target=\"_blank\">scientistsagainstmalaria.net<\/a>)<\/p>\n<p><strong>Statistics of OBPs from <em>Anopheles darlingi<\/em>:<\/strong><\/p>\n<table style=\"height: 34px;\" border=\"\u00bb1\u2033\" width=\"600\" cellspacing=\"\u00bb0\u2033\" cellpadding=\"\u00bb0\u2033\">\n<tbody>\n<tr style=\"text-align: center;\">\n<td><\/td>\n<td>\n<form action=\"\/cgi-bin\/mobpdb\/resultat_sql.cgi\" method=\"post\">\n<button name=\"sql_query\" type=\"submit\" value=\"select * from proteins_v3 where Class like 'Classic%' and ID like 'ADAC%'\">Classic<\/button><br \/>\n<\/form>\n<\/td>\n<td>\n<form action=\"\/cgi-bin\/mobpdb\/resultat_sql.cgi\" method=\"post\">\n<button name=\"sql_query\" type=\"submit\" value=\"select * from proteins_v3 where Class like 'PlusC%' and ID like 'ADAC%'\">PlusC<\/button><br \/>\n<\/form>\n<\/td>\n<td>\n<form action=\"\/cgi-bin\/mobpdb\/resultat_sql.cgi\" method=\"post\">\n<button name=\"sql_query\" type=\"submit\" value=\"select * from proteins_v3 where Class like 'Two%' and ID like 'ADAC%'\">Two-domains*<\/button><br \/>\n<\/form>\n<\/td>\n<td>\n<form action=\"\/cgi-bin\/mobpdb\/resultat_sql.cgi\" method=\"post\">\n<button name=\"sql_query\" type=\"submit\" value=\"select * from proteins_v3 where Class like 'NA%' and ID like 'ADAC%'\">ND<\/button><br \/>\n<\/form>\n<\/td>\n<td>Total<\/td>\n<\/tr>\n<tr style=\"text-align: center;\">\n<td>Number of OBPs<\/td>\n<td style=\"text-align: center;\">21<\/td>\n<td style=\"text-align: center;\">10<\/td>\n<td style=\"text-align: center;\">4<\/td>\n<td style=\"text-align: center;\">0<\/td>\n<td style=\"text-align: center;\">35<\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/?page_id=409\" target=\"_blank\">N\u00b0 with atomic structures (in PDB)<\/a><\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<td style=\"text-align: center;\">&#8211;<\/td>\n<td style=\"text-align: center;\">&#8211;<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<\/tr>\n<tr>\n<td>3D models<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<td style=\"text-align: center;\">&#8211;<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<\/tr>\n<tr>\n<td>Docking results**<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<td style=\"text-align: center;\">&#8211;<\/td>\n<td style=\"text-align: center;\">NA<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><font size = \"1\">*(also known as <em>duplex<\/em> or <em>atypical<\/em>)<br \/>\n**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)<br \/>\nND : undetermined<br \/>\nNA : Not Available<\/font><\/p>\n<table width=\"100%\">\n<tr>\n<td>\n<p>\n<strong>Search the <span style=\"color: #3366ff;\">genomic<\/span> database for all OBP genes from <em>Anopheles darlingi<\/em><\/strong><\/p>\n<form action=\"\/cgi-bin\/mobpdb\/motclef.cgi\" method=\"post\">\n<button name=\"smalldialogue\" type=\"submit\" value=\"ADAC\">Browse genomic data<\/button><br \/>\n<\/form>\n<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<strong>Modelled structures of <em>Classic<\/em> OBP from <em>Anopheles darlingi<\/em><\/strong><\/p>\n<form action=\"\/cgi-bin\/mobpdb\/resultat_sql.cgi\" method=\"post\">\n<button name=\"sql_query\" type=\"submit\" value=\"select ID, Name, Uniprot, Class, Cluster from proteins_v3 where Class = 'Classic' and Name like 'ADAC%'\">Browse models<\/button><br \/>\n<\/form>\n<\/p>\n<\/td>\n<\/tr>\n<\/table>\n<p>\n<strong>Please cite<\/strong><br \/>\n<FONT size=\"1pt\"><a href=\"http:\/\/gbe.oxfordjournals.org\/content\/5\/1\/163.long\" target=\"_blank\">Manoharan M, Ng Fuk Chong M, Va\u00eftinadapoul\u00e9 A, Frumence E, Sowdhamini R, Offmann B. Comparative genomics of odorant binding proteins in Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. <em>Genome Biol Evol.<\/em> 2013;<strong>5<\/strong>(1):163-80.<\/a><br \/>\n<\/FONT>\n<\/p>\n<p><strong>Bibliographic references :<\/strong><\/p>\n<ol>\n<span style=\"font-size: x-small;\"> <\/p>\n<li>Hiwat and Bretas:Ecology ofAnopheles  darlingi Root with respect to vector importance: a review. Parasites &#038; Vectors 2011, 4:177<\/li>\n<li>Moreno M, Marinotti O, Krzywinski J, et al. Complete mtDNA genomes of Anopheles darlingi and an approach to anopheline divergence time. Malaria Journal. 2010;9:127. doi:10.1186\/1475-2875-9-127.<\/li>\n<p><\/span>\n<\/ol>\n<p><!--\n\n\n<form action=\"\/cgi-bin\/mobpdb\/motclef3.cgi\" method=\"post\">  \n<textarea id =\"smallrecherche\" rows=\"1\" cols=\"10\" name=\"smalldialogue\" style=\"font-family : courier\" >ADACOBP<\/textarea> <input type=\"submit\" value=\"Submit request\" \/>\n<\/form>\n\n\n--><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anopheles darlingi is a major malaria vector in the Americas. Its broad geographical distribution, ranging from southern Mexico to northern Argentina, is coupled with a high morphological, behavioral and genetic diversity. Support for considerable genetic variation within this taxon comes from the analysis of polytene chromosomes, isozymes, as well as nuclear and mitochondrial DNA markers. [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":9,"menu_order":8,"comment_status":"closed","ping_status":"closed","template":"page-without-sidebar.php","meta":{"footnotes":""},"class_list":["post-599","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=\/wp\/v2\/pages\/599","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=599"}],"version-history":[{"count":10,"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=\/wp\/v2\/pages\/599\/revisions"}],"predecessor-version":[{"id":775,"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=\/wp\/v2\/pages\/599\/revisions\/775"}],"up":[{"embeddable":true,"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=\/wp\/v2\/pages\/9"}],"wp:attachment":[{"href":"https:\/\/protsci-us2b.univ-nantes.fr\/mobpdb\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=599"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}