Anopheles melas

March 31st, 2023

Anopheles melas belongs to the Anopheles gambiae species complex, which consists of at least seven species, and it is a locally important vector in coastal western Africa. An. melas is commonly associated with brackish water and can utilise saline environments, yet does not appear to require brackish water for larval stage development.Unlike other African dominant vector species, the density fluctuations of An. melas are closely associated with tidal changes rather than seasons, and a peak in adult numbers 11 days after spring tides has been recorded. An. melas is generally considered to be a vector of lesser importance where it occurs in in the same places as An. gambiae or An. arabiensis. However, in coastal areas, where it can occur in very high densities, it is still a problematic vector of malaria. Its genome was sequenced to 2016 [1].

(source & for more information : Vectorbase)

Statistics of OBPs from Anopheles melas:





Total
Number of OBPs 24 15 12 3 54
N° with atomic structures (in PDB) NA NA NA
3D models NA NA NA NA
Docking results** NA NA NA NA

*(also known as duplex or atypical)
**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)
ND :undetermined
NA : Not Available

Search the genomic database for all OBP genes from Anopheles melas


Modelled structures of Classic OBP from Anopheles melas


Please cite
Manoharan M, Ng Fuk Chong M, Vaïtinadapoulé A, Frumence E, Sowdhamini R, Offmann B. Comparative genomics of odorant binding proteins in Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Genome Biol Evol. 2013;5(1):163-80.

Bibliographic references

  1. Deitz KC, Athrey GA, Jawara M, Overgaard HJ, Matias A, Slotman MA. Genome-Wide Divergence in the West-African Malaria Vector Anopheles melas. G3: Genes|Genomes|Genetics. 2016;6(9):2867-2879. doi:10.1534/g3.116.031906.
  2. Sinka ME, Bangs MJ, Manguin S, et al. The dominant Anopheles vectors of human malaria in Africa, Europe and the Middle East: occurrence data, distribution maps and bionomic précis. Parasites & Vectors. 2010;3:117. doi:10.1186/1756-3305-3-117.

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