Anopheles dirus
The Anopheles dirus complex includes non-vector and vector species of human malaria. Anopheles dirus (formerly A. dirus species A) is distributed in eastern Asia (Myanmar, Thailand, Cambodia, Laos, Vietnam, and Hainan Island in China) in forested zones. It is often seen as a species complex including at least seven [2][3] closely related and efficient forest-based malaria vectors in Asia. Hence, its geographical distribution is overlapping with areas of high malaria prevalence rates and the occurrence of drug resistant Plasmodium falciparum [4]. P. falciparum is one of the four main protozoan parasites that cause malaria and is one of the leading causes of malaria deaths. This species complex is of high medical importance for malaria control, in view of the biological specificities of the members of this complex. Sympatric sibling species of the complex differ in types of larval habitat, seasonality and behaviour. These differences also exist within the species suggesting the role of environmental factors in determining these[1]. Its genome was sequenced in 2009.
(source & for more information : Vectorbase , Wikipedia )
Statistics of OBPs from Anopheles dirus:
| Total | |||||
| Number of OBPs | 23 | 15 | 8 | 1 | 47 |
| N° with atomic structures (in PDB) | NA | NA | – | – | NA |
| 3D models | NA | NA | NA | – | NA |
| Docking results** | NA | NA | NA | – | NA |
*(also known as duplex or atypical)
**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)
ND : undetermined
NA : Not Available
| Search the genomic database for all OBP genes from Anopheles dirus |
| Modelled structures of Classic OBP from Anopheles dirus |
Bibliographic references
- Obsomer, Valerie; Defourny, Pierre; Coosemans, Marc (2007). “The Anopheles dirus complex: spatial distribution and environmental drivers”. Malaria journal. 6 (26): 1474–2875. doi:10.1186/1475-2875-6-26. PMC 1838916 Freely accessible. PMID 17341297. Retrieved 2007-08-05.
- Dash AP, Adak, T., Raghavendra, K., Singh, OP. (2007) The biology and control of malaria vectors in India. Current Science 92(11). p.1574 PDF.
- Peyton EL. 1989. A new classification for the Leucosphyrus group of Anopheles (Cellia). Mosq. Syst. 21:197–205.
- Yang TH (1983) A review of literature on Anopheles balabacensis balabacensis. World Health Organization. WHO/MAL/83.999, WHO/MAL/83.873M.
- Hittinger CT, Johnston M, Tossberg JT, Rokas A. Leveraging skewed transcript abundance by RNA-Seq to increase the genomic depth of the tree of life. Proceedings of the National Academy of Sciences of the United States of America. 2010;107(4):1476-1481. doi:10.1073/pnas.0910449107.