Anopheles minimus

March 31st, 2023

The Anopheles minimus complex includes A. minumus sensu stricto (formerly A. minimus A), which is located from northern India eastwards through Vietnam and northward across southern China, including Taiwan. Anopheles minumus sensu stricto is one of the main malaria vectors in the mainland of Southeast Asia. Larvae are generally found in small to moderate-sized streams or canals with slow running, clear and cool water, partially shaded and with grassy margins where females prefer to lay their eggs. They develop in various pools (rock, ground, stream and seepage). The adult behaviour of An. minimus s.l. is reported as highly diverse for two main reasons: (1) most studies do not differentiate An. minimus and An. harrisoni and (2) these two species are highly opportunistic in their habits, exhibiting considerable behavioural and ecological plasticity. Females of An. minimus mainly bite humans (up to 93% in Assam, India), but the degree of anthropophily/zoophily depends on the availability of alternative hosts (e.g. cattle). An. minimus and An. harrisoni, are vectors of malaria parasites throughout their respective distributions, although further investigation needs to be conducted on An. harrisoni as its role in malaria transmission appears weaker than that of An. minimus, despite it being reported as a main vector in China. An. minimus s.l. is considered a primary malaria vector in the hilly forested regions of mainland Southeast Asia. Its genome was sequenced in 2012.
(source & for more information : Vectorbase)

Statistics of OBPs from Anopheles minimus:





Total
Number of OBPs 22 16 11 2 51
N° with atomic structures (in PDB) NA NA NA
3D models NA NA NA NA
Docking results** NA NA NA NA

*(also known as duplex or atypical)
**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)
ND : undetermined
NA : Not Available

Search the genomic database for all OBP genes from Anopheles minimus


Modelled structures of Classic OBP from Anopheles minimus


Please cite
Manoharan M, Ng Fuk Chong M, Vaïtinadapoulé A, Frumence E, Sowdhamini R, Offmann B. Comparative genomics of odorant binding proteins in Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Genome Biol Evol. 2013;5(1):163-80.

Bibliographic references :

  1. Genome Analysis Of Vectorial Capacity In Major Anopheles Vectors Of Malaria Parasites
    Authors: Nora J. Besansky, Anopheles Genomes Cluster Committee
  2. Sinka, M.E., Bangs, M.J, Manguin, S., Chareonviriyaphap, T., Patil, A.P., Temperley, W.H., Gething, P.W., Elyazar, I.R.F., Kabaria, C.W., Harbach, R.E. and Hay, S.I. (2011). The dominant Anopheles vectors of human malaria in the Asia-Pacific region: occurrence data, distribution maps and bionomic précis. Parasites and Vectors 4: 89

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