Anopheles maculatus

March 31st, 2023

Anopheles maculatus complex includes important malaria vectors distributed from the Indian subcontinent through Southeast Asia to Taiwan. Anopheles maculatus B is a vector member of this complex. Members of the Maculatus Group are typically found in or near hilly and mountainous areas. Larvae have been collected in a diverse number of permanent or semi-permanent bodies of clean water that are often exposed to direct sunlight, including ponds, lakes, swamps, ditches, wells, different types of pools. In general, females are more strongly attracted to cattle than humans, but freely bite people both inside and outside houses. An. maculatus and An. sawadwongporni appear to be the least zoophilic of the species and exhibit early biting activity, peaking between 18:00 and 21:00. Its genome was sequenced in 2012 [1].
(source & for more information : Vectorbase)

Statistics of OBPs from Anopheles maculatus:





Total
Number of OBPs 21 9 12 0 42
N° with atomic structures (in PDB) NA NA NA
3D models NA NA NA NA
Docking results** NA NA NA NA

*(also known as duplex or atypical)
**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)
ND : undetermined
NA : Not Available

Search the genomic database for all OBP genes from Anopheles maculatus


Modelled structures of Classic OBP from Anopheles maculatus


Please cite
Manoharan M, Ng Fuk Chong M, Vaïtinadapoulé A, Frumence E, Sowdhamini R, Offmann B. Comparative genomics of odorant binding proteins in Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Genome Biol Evol. 2013;5(1):163-80.

Bibliographic references :

  1. Genome Analysis Of Vectorial Capacity In Major Anopheles Vectors Of Malaria Parasites
    Authors: Nora J. Besansky, Anopheles Genomes Cluster Committee
  2. Sinka, M.E., Bangs, M.J, Manguin, S., Chareonviriyaphap, T., Patil, A.P., Temperley, W.H., Gething, P.W., Elyazar, I.R.F., Kabaria, C.W., Harbach, R.E. and Hay, S.I. (2011). The dominant Anopheles vectors of human malaria in the Asia-Pacific region: occurrence data, distribution maps and bionomic précis. Parasites and Vectors 4: 89

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