Aedes aegypti

May 16th, 2018

Aedes_aegyptiAedes aegypti known as yellow fever mosquito is a mosquito that can spread yellow fever viruses, the dengue fever, Chikungunya and other diseases. It can be recognized by white markings on legs and a marking in the form of a lyre on the thorax. The mosquito originated in Africa but is now found in tropical and subtropical regions throughout the world. The genome of this species of mosquito was sequenced and published in 2007.

Statistics of OBPs from Aedes aegypti:




Total
Number of OBPs 39 27 45 111
N° with atomic structures (in PDB) 1 1
3D models

36
Docking results** 36 x 126 = 4536
4536

*(also known as duplex or atypical)
**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)


Search the genomic database for all OBP genes from Aedes aegypti


Modelled structures of Classic OBP from Aedes aegypti


Download of fasta sequences of all OBPs from Aedes aegypti :
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Please cite
Manoharan M, Ng Fuk Chong M, Vaïtinadapoulé A, Frumence E, Sowdhamini R, Offmann B. Comparative genomics of odorant binding proteins in Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Genome Biol Evol. 2013;5(1):163-80.

Other bibliographic reference(s):
Zhou, J.J., He, X.L., Pickett, J.A., and Field, L.M. 2008. Identification of odorant-binding proteins of the yellow fever mosquito Aedes aegypti: genome annotation and comparative analyses. Insect Molecular Biology 17: 147-163.

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