Anopheles funestus

March 31st, 2023

Anopheles funestus has a wide geographic distribution, extending throughout Africa where is one of the most important vectors of malaria. A typical An. funestus larval habitat is a large, permanent or semi-permanent body of fresh water with emergent vegetation, such as swamps, large ponds and lake edges. Larvae have been found in shaded and sunlit environments where An. funestus may use emergent vegetation as refuge against predation while the shading it casts, or the presence of shade from overhanging plants, is of lesser importance. In some areas, An. funestus larvae are associated with rice cultivation (e.g. Madagascar, Mali) and replaces An. arabiensis in a successive temporal process during rice plant growth, exhibiting higher densities in older, maturing fields compared to the preceding open conditions preferred by An. arabiensis. An. funestus is a highly adaptable species, allowing it to occupy and maintain its wide distribution and utilise and conform to the many habitat types and climatic conditions contained therein. Its genome was sequenced in 2012.

(source & for more information : Vectorbase)

Statistics of OBPs from Anopheles funestus:





Total
Number of OBPs 24 15 12 5 56
N° with atomic structures (in PDB) NA NA NA
3D models NA NA NA NA
Docking results** NA NA NA NA

*(also known as duplex or atypical)
**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)
ND :undetermined
NA : Not Available

Search the genomic database for all OBP genes from Anopheles funestus


Modelled structures of Classic OBP from Anopheles funestus


Please cite
Manoharan M, Ng Fuk Chong M, Vaïtinadapoulé A, Frumence E, Sowdhamini R, Offmann B. Comparative genomics of odorant binding proteins in Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Genome Biol Evol. 2013;5(1):163-80.

Bibliographic references

  1. Sinka, M.E., Bangs, M.J., Manguin, S., Coetzee, M., Mbogo, C.M., Hemingway, J., Patil, A.P., Temperley, W.H., Gething, P.W., Kabaria, C.W., Okara, R.M., Boeckel, T.V., Godfray, H.C.J., Harbach, R.E. and Hay, S.I. (2010). The dominant Anopheles vectors of human malaria in Africa, Europe and the Middle East: occurrence data, distribution maps and bionomic précis. Parasites & Vectors, 3: 117

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