Anopheles stephensi
Anopheles stephensi Liston is a major malaria vector with a geographical range from the Middle East through the Indian subcontinent and China. Throughout its natural range, Anopheles stephensi is an important vector for both Plasmodium falciparum and Plasmodium vivax. The strain used for this genome sequencing project is the Indian Wild Type strain originally established at the Walter Reed Army Institute of Research. It belongs to the “type” biological form and has a segregating 2Rb inversion. An. stephensi is recognised as an important vector of malaria in urban areas bordering the Persian Gulf, including western and northwestern India. There are three known forms of An. stephensi including the typical form which is an efficient vector of urban malaria, the intermediate form, which is typically found in rural villages and peri-urban areas, but very little is known about its vector status, and the mysorensis form which is restricted to rural areas with poor vectorial capacity due to its highly zoophilic behaviour. The mysorensis form is, however, considered an important vector in Iran. Its genome was sequenced in 2014 [1]
(source & for more information : Vectorbase)
Statistics of OBPs from Anopheles stephensi:
| Total | |||||
| Number of OBPs | 27 | 15 | 10 | 1 | 53 |
| N° with atomic structures (in PDB) | NA | NA | – | – | NA |
| 3D models | NA | NA | NA | – | NA |
| Docking results** | NA | NA | NA | – | NA |
*(also known as duplex or atypical)
**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)
ND : undetermined
NA : Not Available
| Search the genomic database for all OBP genes from Anopheles stephensi |
| Modelled structures of Classic OBP from Anopheles stephensi |
Bibliographic references :
- Jiang X, Peery A, Hall AB, et al. Genome analysis of a major urban malaria vector mosquito, Anopheles stephensi. Genome Biology. 2014;15(9):459. doi:10.1186/s13059-014-0459-2.
- Genome Analysis Of Vectorial Capacity In Major Anopheles Vectors Of Malaria Parasites
Authors: Nora J. Besansky, Anopheles Genomes Cluster Committee - Sinka, M.E., Bangs, M.J, Manguin, S., Chareonviriyaphap, T., Patil, A.P., Temperley, W.H., Gething, P.W., Elyazar, I.R.F., Kabaria, C.W., Harbach, R.E. and Hay, S.I. (2011). The dominant Anopheles vectors of human malaria in the Asia-Pacific region: occurrence data, distribution maps and bionomic précis. Parasites and Vectors 4: 89