Anopheles merus

March 31st, 2023

Anopheles merus belongs to the Anopheles gambiae species complex, which consists of at least seven species, and it is a locally important vector in eastern and southern Africa where it is mainly found along the coast. An. merus is found in high numbers in shallow brackish pools and marsh or swamp areas along the coast. As a consequence, this species does not exhibit density changes in response to tidal fluctuations nor does it appear to tolerate very high levels of salinity. An. merus is generally opportunistic in host selection, depending on host availability and females have a tendency to bite and rest outdoors. An. merus has previously been considered as only a minor or unimportant vector, however, it has been identified as playing an unexpectedly important role along the Tanzanian coast and more recently in Mozambique. Its genome was sequenced in 2012 [1]

(source & for more information : Vectorbase)

Statistics of OBPs from Anopheles merus:





Total
Number of OBPs 25 16 13 0 54
N° with atomic structures (in PDB) NA NA NA
3D models NA NA NA NA
Docking results** NA NA NA NA

*(also known as duplex or atypical)
**(molecular docking was performed on 126 odorants that are known repellants and attractants for mosquitoes)
ND : undetermined
NA : Not Available

Search the genomic database for all OBP genes from Anopheles merus


Modelled structures of Classic OBP from Anopheles merus


Please cite
Manoharan M, Ng Fuk Chong M, Vaïtinadapoulé A, Frumence E, Sowdhamini R, Offmann B. Comparative genomics of odorant binding proteins in Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Genome Biol Evol. 2013;5(1):163-80.

Bibliographic references :

  1. Genome Analysis Of Vectorial Capacity In Major Anopheles Vectors Of Malaria Parasites
    Authors: Nora J. Besansky, Anopheles Genomes Cluster Committee
  2. Sinka ME, Bangs MJ, Manguin S, et al. The dominant Anopheles vectors of human malaria in Africa, Europe and the Middle East: occurrence data, distribution maps and bionomic précis. Parasites & Vectors. 2010;3:117. doi:10.1186/1756-3305-3-117.

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